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In both trials, the primary evidence was the confession of a co-defendant -- the leader of each plot.
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In both phase III trials, the primary endpoint was achieved in a significantly greater proportion of patients treated with the 10 mg/kg dosage compared to patients treated with placebo (P = 0.0006 in BLISS-52 and P = 0.02 in BLISS-76).
Both trials tested the primary hypothesis that Si uptake and cane yield following fertilization with Ca2SiO4 would be differentially affected by simultaneous treatment of plants with either N H 4 + (rhizosphere acidification) or N O 3 − (rhizosphere alkalinization) as N-form treatments.
For radiotherapy and chemoradiotherapy phase I trials, the primary endpoint must reflect both effectiveness and potential treatment toxicities.
For late-stage trials, the primary analysis is often subject to sensitivity analysis to address this.
In this trial, the primary outcome is the proportion of patients who achieve a BP < or =140/90 mm Hg at each outpatient clinic visit over 24 months.
Because the proposed study is a prevention trial, the primary measure is 'occurrence of delirium'.
For the cardiovascular trial, the primary outcome is cardiovascular risk status 12 months following randomisation.
However, in this trial, the primary treatment was administered only for 3 months.
For each disease, we separated trials targeting the primary infection from trials examining disease complications.
In both trials our primary outcome measure will be quantity of alcohol consumed at 12 months after randomisation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com