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Both treatment groups achieved similar improvements based on change in the PANSS total score.
It should be noted that in this study both treatment groups achieved satisfactory cooling in under 1 hour.
About 70% of patients in both treatment groups achieved endoscopic remission, and 35% in the OD group and 41% in the TID group achieved histological remission.
However, both treatment groups achieved satisfactory cooling in less than 1 hour using a body-cooling unit, which was obviously the key therapeutic procedure in this study [ 9].
Both treatment groups achieved comparable reductions from baseline in HbA1c level, with adjusted mean HbA1c approaching 7.0% after 12 weeks of treatment.
Both treatment groups achieved similar improvements in pain and function, and the percentage of complications was comparable to that in other studies [ 33– 33].
Similar(51)
Similar proportions of patients in the two treatment groups achieved the target HbA1c below 7.0% or 6.5%.
Children in the continuous budesonide and budesonide/placebo treatment groups achieved a mean PIFTBH of 60 l/min during the study period.
Based on the cell counts findings, the cell viability of all maltodextrin treatment groups achieved 100% viability rate, except for RBLA treatment, which only showed the cell viability at the rate of 93%.
It is notable that all three treatment groups achieved a median OS of >13 months, the longest reported to date in this nonsquamous NSCLC patient population and well beyond the historical survival benchmark of 1 year.
When the thickness and volume of the cartilage were measured (both micro-CT and histomorphometry) all the treatment groups achieve scores halfway between negative and positive controls, but without statistical differences.
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