Sentence examples for both transactivation and repression from inspiring English sources
Thus, the DBD, LBD and AF2 domains, but not the AF1 domain, are critical for both transactivation and repression by LXR.
DISC1 inhibits both the transactivation and repression (3) activities of ATF4, and is thus likely to be an important modulator of ATF4-mediated transcription in the brain.
The different isoforms of AP-2α possess differential transactivation and repression activities which are dependent on the promoter context.
The regularity and amplitude of the cAMP pulse could affect the level of nuclear active GtaC, which would have major consequences for the transactivation and repression of certain genes [ 78].
Inactivation of p53 affects both transactivation and transrepression to alter cell growth.
In the FoxA cluster conserved domain II has been shown to be involved in transactivation [ 36] and repression [ 37] in rat FoxA2.
By contrast, Δ133p53 is devoid of both transactivation domains and part of the DNA-binding domain.
Histone methylations are linked to both transcriptional activation and repression.
Thus, SNF1 both promotes and attenuates repression.
YY1 is a sequence-specific DNA binding C2H2 zinc finger protein that contains both a transactivation domain and a repression domain [4], [5].
