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In fibroblasts, both these pathways contribute to LPL internalization [ 38].
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TAK1 affects both canonical and non-canonical BMP signal transduction and we found that both of these pathways contribute to BMP2-mediated Sox9 promoter activation.
Thus, we investigated whether any of these pathways contribute to the function of Set2 after DSB.
The Means Laboratory is interested in the study of cell signaling cascades that regulate cell proliferation, differentiation, or function and how alterations in these pathways contribute to oncogenesis.
This indicates that these pathways contribute redundant (correlated) information for sample classification.
Reactions in these pathways contribute to chemosensitivity in cancer.
Therefore, these pathways contribute to study the mechanisms of drugs and drug-repurposing.
Mechanisms by which these pathways contribute to disease in mouse models and patients are under active investigation.
The mechanism of how these pathways contribute to apoptosis in p53-deficient cells is not entirely clear.
Next, we analyze how these pathways contribute to the overall similarity/dissimilarity of human tissues with yeast.
Because activation of these pathways modulates cell survival and chemoresistance, it is conceivable that activation of these pathways contributes to TRAIL resistance.
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