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Non‐viral gene therapy can be realized by optimization of the pharmacokinetic properties of both the vector and the encoded therapeutic protein.
This shows that homologous recombination can be substantially enhanced if homologous single loxP sites are included in both the vector and the host and in the presence of Cre recombinase.
Of note, much higher virus yields obtained by modern techniques cannot be directly compared to our data since they are typically obtained either from individually selected high-producing clones or from cells harboring a high copy number of both the vector and the packaging constructs.
Vector-pathogen interactions involve traits from both the vector and the pathogen [ 5].
In addition, AmphoB modestly decreased the relative acidity of both the vector and IFITM3 cell lines.
The tumorigenic effect of endocan was clearly confirmed, independently of both the vector and the subtype of 293 cells used.
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Therefore, if transcription continues through the LTR, and the splice donor site ends up matched with an appropriate splice acceptor, then the polyadenylation signal of the LTR could be lost during splicing, and a stable hybrid transcript encompassing both the vector-and host-derived sequences could be formed.
The fact that lifespan and density do not contribute to the variation in seroprevalence may reflect the ecological ubiquity of the vectors and the fact that the virus circulates easily in both the vectors and the host populations (16 ).
Hepatic insulin production resulted in the reduction of blood glucose in treated diabetic rats, the degree of blood glucose reduction correlated with both the vector dose and the level of hepatic insulin expression.
Inspired by the above observations, in this paper, the optimality conditions are established for problem (P) in both the vector criterion and set criterion by using Studniarski derivatives.
We have studied the optimality conditions for both the vector criterion and set criterion for a set-valued optimization problem in this note.
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