Indeed, TF co-associations were identified based on ChIP-seq peak-binding overlaps in C. elegans modENCODE studies (Araya et al., 2014), but the underlying sequence recognition mechanisms were not apparent.
HTS data is highly non-uniform in coverage which is influenced by GC content of the underlying sequence where both very high and very low GC content DNA sequence is captured by fewer HTS reads (Dohm et al. 2008).
Mismatches and gaps were counted, and the latter gaps were categorized for the nature of the underlying sequence.
Remark 3.6 Compactness of the underlying sequence space is useful for establishing strong convergence of an approximant of a fixed point.
Epigenetics is the study of mechanisms, other than alterations in the underlying sequence of DNA, that control a gene's expression.
GeneTag™ is a novel expression profiling method that allows the visualization, quantification and identification of expressed genes whether known or novel in any species, tissue or cell type, independent of knowledge of the underlying sequence.
Considering the same model in (11), find the control that induces the spiking in the two neurons according to the times specified in the target pattern (varSigma_{P}), constrained by the underlying sequence.
The popular 'zinc-finger model' proposed that the CTCF's different functions are due to the interplay between the zinc-finger engagement and the underlying sequence differences (Ohlsson et al., 2001).
Complex genomes contain many repetitive sequences that make it more challenging to assemble the reads into the underlying sequence.
These include the rate of presentation, the number of trials, and the structure of the underlying sequence.
