Sentence examples for both the phosphorylation of from inspiring English sources

As a consequence, both, the phosphorylation of SMAD proteins as well as the upregulation of connective tissue growth factor (CTGF), are associated with the activation of the TGF-β pathway [54].

These results show that AND induced both the phosphorylation of p53 and p53 activation.

Furthermore, prion infection greatly increased both the phosphorylation of cPLA2 and prostaglandin E2 production.

As shown in Figure 8, SP600125 prevented both the phosphorylation of JNK and the expressions of cytosolic cytochrome c and cleaved-caspase-3.

Both the phosphorylation of the adaptor FRS2, the kinetics (sustained or transient) of phosphorylation of p42/44 MAPK) are varied, and so differing cellular responses are produced.

Furthermore, an increase was found in both the phosphorylation of AKT and mammalian target of rapamycin (mTOR) (Fig. 6E and F) in the human myoblasts following exposure to E2.

Figure 4 shows that the EGFR kinase inhibitor, AG1478, and the MEK inhibitor, AZD6244, both inhibited the phosphorylation of ERK1/2 induced by both DHA and EPA in SCC-25 cells.

Thus, NS-018 both inhibited the phosphorylation of components of JAK2-mediated signaling and induced apoptosis in cell lines whose growth depended on JAK2 activation.

In the presence of both mAbs, the phosphorylation of AKT but not that of ERK1,2 was inhibited, and the inhibition of colony formation induced by each mAb was additive (data not shown).

Although CcpA binds to DNA as a complex with HPr-Ser46-P, FBP is required both for the phosphorylation of HPr by the HPr kinase and for the formation of the CcpA/HPr-Ser46-P complex [ 40, 41].

Another study constructed a lentivirus vector and performed dual-luciferase reporter assays to confirm that miR-29a could target SPARC and thereby both inhibit the phosphorylation of SPARC/AKT/mTOR and HCC growth [[ 102]].