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Both the partition coefficient P(o/w), which is defined as the molar concentration ratio of a single species A between n-octanol and water at equilibrium, and logP(o/w), which is an important parameter used to characterize lipophilicity of a compound, were calculated.
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The partition coefficient for both metallacarborane bearing thymidine conjugates 5 and 6 was more than 500 times higher than that of unmodified nucleoside.
For the error in the partition coefficient, both the ATB and CBF were affected when calculated by BFMAT; however, the degree of error in CBF was smaller than that computed by BFMF and the same as that by ARG (Figure 5D).
The partition coefficient depends on the identity of both mobile and stationary phases.
The predictions are in good agreement with experiments, and both show that the partition coefficients decrease with increasing the number of carbon atoms in the alcohols.
The partition coefficient was very sensitive to surfactant formula.
We report here that cholinergic ligands induce changes in the partition coefficient of the hydrophobic cation tetraphenylphosphonium (TPP) into AChR-enriched membranes.
The compound's lipophilicity, expressed as a quantity known as logP (the logarithm of the partition coefficient between water and 1-octanol), is less than 5.
The partition coefficient of -[125I]IV-OH was measured.
The partition coefficient was determined by shake flask method.
The partition coefficient (PC) was calculated using Eq. (1).
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