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However, both the molecular function and the disease relevance of the spliced lncRNA 116HG are unknown.
GO analysis revealed both the molecular function and biological process of the differentially expressed proteins (Graph S1).
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Among the enriched biological processes (Fig. 3e) and molecular functions (Fig. 3f) in both species, the molecular function "catalytic activity" is among the most significant (p < 1e-4).
Both the molecular functions and the disease relevance of these regulators in the nervous system will be discussed.
Gene Set Enrichment Analysis was performed to check whether the a priori defined set of genes shows a differential pattern in both the biological process and the molecular function states.
To proof such a hypothesis, the molecular function of both genes need first to be characterised.
(b) Performance evaluation in the Molecular Function category.
In the Molecular Function category, performance may be considered accurate.
The molecular function associated to Dp427 was channel activity and transmembrane transporter activity.
For the Molecular function category, the most highly represented genes were associated with "binding" and "catalytic activity".
Within the Molecular Function terms, none of the methods predicted poly(U) or poly(G) RNA binding43 or microRNA binding.
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