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Both the low dose of STZ and the high fat diet are essential elements to induce type 2 diabetes with insulin resistance.
μstatic,Neq varied with test lubricant and Tps in both the low dose sequence (p < 0.001, p < 0.05, Fig. 2a) and high dose sequence (p < 0.001, p < 0.001, with an interaction between the effects of lubricant and Tps on μstatic,Neq (p < 0.01), Fig. 2b).
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Both doses effectively induced diabetes, but the low dose did not appear to exhibit toxic effects.
There is need for optimization of starting doses for both the low-dose step-up and step-down protocols.
On the other hand, there was no significant difference between first and second PET scans in both the low-dose group and the control group.
For both the low-dose and high-dose T exposed cells, the 30 min data is presented based on preliminary experiments which suggested that at this time point the phosphorylation status of IRS1 Ser636/639 and S6k plateaued, Akt reached its peak phosphorylation, and mTOR phosphorylation remained unchanged.
Four subjects experienced presyncope during both the low-dose and high-dose tilts.
The serum sphinganine level and the sphingosine/sphinganine ratio, monitored toward the end of the experiment, significantly increased in both the low-dose and high-dose animals.
Cardwell et al (2014) focussed solely on low-dose aspirin usage while Walker et al (2012) analysed both the low-dose aspirin usage and high-dose aspirin usage.
All of the interval cancer cases for both the low-dose CT group and the chest X-ray group were smokers.
Both the low-dose ITI protocol and the Bonn ITI protocol generate more health benefit (more QALYs) than both the Malmö ITI protocol and the on-demand protocol with rFVIIa but at a different cost.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com