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There exists an inherent penalty in this type of algorithms at both the initial step and the final step.
Our results support this observation and associate the inhibitory effects of S. mitis to both the initial step as well as the ensuing multiplication ability of A. actinomycetemcomitans.
Pah1 phosphorylation and inactivation occur at the G2/M transition of the cell cycle, indicating that a window exists during the cell cycle in which both the initial step of lipogenesis and lipolysis may operate in parallel.
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Comparison of TdPI with a shortened variant lacking the flexible prehead and posthead segments revealed that these regions do not contribute to the protein conformational stability or the inhibition of trypsin but are important for both the initial steps of the folding reaction and the inhibition of tryptase β.
In particular, genistein has proven to be a valuable tool for the inhibition of cancer metastasis, exerting effects on both the initial steps of primary tumor growth as well as the later steps of the metastatic cascade.
To achieve both these goals, the initial step is to construct their networks based on versatile biological information and to analyze such networks.
Extraction, which refers to the removal of the relevant information from the text and its assignment to appropriate categories, was both the focus and the initial step.
In particular, decreased expression was observed for key enzymes in β-oxidation including acyl-CoA dehydrogenase (Acads, -1.4 fold in both models), which catalyzes the initial step in each cycle of β-oxidation; and acetyl-CoA acyltransferases (Acaa1 and Acaa1b, both genes: -1.3 fold in WT, -1.6 fold in PXR-KO), which catalyze the final step of the β-oxidation cycle.
Regardless of the different distance computation algorithms, the initial step of both TOPSIS algorithms is to form a committee with K numbers of decision makers to conduct the assessment process.
The initial step of both forms of NHEJ is the formation of one or more DNA double-strand breaks, which may arise spontaneously or be induced, for example, by ionizing radiation or errors during DNA replication.
The initial step of both pathways involves an in vitro conversion of rPrP into an amyloid fibrilar state.
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