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It costs $25,000 annually, which covers both the initial development fee and the expense of keeping the information up-to-date.
The molecular mechanisms, which control both the initial development and subsequent maintenance of these critical microenvironments, are poorly defined.
Epigenetic and genetic alterations have long been thought of as two related mechanisms in both the initial development and in breast cancer progression [ 4].
However, psychosocial factors are also believed to be important for both the initial development of MSDs and the long-term disability that may follow [ 18– 22].
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The inclusion of caregivers with a range of educational backgrounds both in the initial development of the conceptual model [ 25] and during this validation research has ensured that the CBQ-HF is understandable to caregivers with varying education and health literacy levels by using caregiver-friendly language.
In zebrafish, inhibition of RA signaling before the end of gastrulation inhibits the initial development of both hepatic and pancreatic endoderm [ 135].
JY developed the NWayComp software and participated in the initial development of the database.
The initial development of the fruiting body is similar in both P. violaceum and D. laterosoum.
He worked on iPhone software from the initial development stage until IOS version 5.1 (2012).
After plans for the initial development became known, "the townspeople put up very strong opposition to the development -- actually to any development," Mr. Jarkow said.
"Novartis is scary; Merck could become scary, Teva as well," Ms. Kulhoff said, noting the threat they pose to the companies that do the initial development of biologics.
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