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Both the inhibition of inflammatory flares and the treatment of hyperuricemia itself are included in the management of gout.
We found that both the inhibition of JNK and, separately, the inhibition of p38 reversed anisomycin-induced cell death in Jurkat and J-DHIV cells, but the absolute difference was greater for J-DHIV cells at anisomycin concentrations near EC50 (Fig. 6c).
It is a pharmacon having a strong trophic-anabolic action on the bone tissue, assuring both the inhibition of the bone loss, and the formation of new bones of good quality.
The results revealed that the origin of protecting the long-range ordered (100) structure by HBr is mainly through the inhibition of oxygen adsorption, while that by CTAB comes from both the inhibition of oxygen adsorption and the CTA+ irreversible adsorption.
These experiments indicated that both the inhibition of feedback by carbenoxolone and by 100 µM Co2+ were not due to non-specific effects on the Ca2+-current of cones, but were an effect of blocking a current in horizontal cells.
Both the inhibition of mGluR1 expression and suppression of both theta and gamma oscillatory activity caused in the dentate gyrus by chronic mGluR5 antagonism appear to contribute importantly to the impairment of initial encoding of sensory information.
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In both systems the inhibition of protein synthesis failed to inhibit the formation of autophagic vacuoles or their subsequent transformation into autolysosomes, as depicted from electron microscopic histochemical preparations.
This suggests a role for both in the inhibition of motor responses.
We show that the TNFα/nSMase/ceramide pathway leads both to the inhibition of Epo-activated erythropoiesis and the activation of myeloid differentiation.
In both studies the inhibition of Abl family kinases by imatinib blocked the infection.
MKK7 and MKK9 were linked both to the inhibition of meristemoid amplifying divisions, and to the promotion of GMC divisions and stomata differentiation [5].
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