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More importantly, "We haven't come across a school district yet that has said it can't afford us," Feuer told me, a nod to both the essentiality of what it's doing, and its pricing.
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Gene knock-outs revealed that both genes were dispensable while the essentiality of other genes in the pathway strongly suggested that the dihydroxy-acid dehydratase activity was required.
The essentiality of both TbSTT3A and TbSTT3B in vivo and their novel specificities (particularly that of TbSTT3A) may offer potential therapeutic targets for future exploitation.
We aimed to determine how the presence of mouse and B. thetaiotaomicron affected the essentiality of genes when both organisms metabolically interact.
With this in mind, in our present study, we utilize both genetic and chemical approaches to assess the essentiality of the enzyme in T. cruzi.
As we share a common belief in the essentiality of free and open discourse both on and off campus, I ask your help in convincing Tufts University President Bacow to overturn this dangerous decision.
The reliable identification of essential genes in a biological network depends on both the network structure and the algorithm used to identify the essentiality of genes.
The biochemical activities of both B. malayi and C. elegans iPGM enzymes have been demonstrated as well as the essentiality of the gene for nematode development.
Both iMLTC806cdf and the network of Bacillus subtilis [ 23] fail to identify the essentiality of CD1536 (yumC in B. subtilis) due to its implication in regulatory processes.
Two multicopy suppressors, ptsN and yhbW, were isolated that suppress both the lethality due to inhibition of σE activity and the essentiality of the rpoE gene.
The essentiality of genes was determined by querying the database of essential of genes [ 31].
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