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A cut-off at 45% OD (see above) was the best compromise to optimise both the concordance of positive results and the concordance of negative results.
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All samples were tested by both assays; the concordance of the enzyme immunoassay and strip immunoblot assay in this study was 97%, and the criterion for seropositivity was a positive reaction in both assays.
For 93 dogs on which PCR was performed on both biological samples the concordance of PCR results was 63.4%.
The primary efficacy endpoint in both studies was the concordance of radioactive lymph nodes identified with [99mTc]tilmanocept and those identified with VBD.
In subjects included in the second survey (n = 685, both followed and incident), the concordance of the two classifications was compared (GINA 1992 vs GINA 2004) at follow-up.
The concordance of both classifications according to the coefficient κ for nominal data is κ =.73.
The use of the fellow eye for comparison also requires exact data on the concordance of both eyes in SD-OCT.
Secondary goal was to assess the concordance of both methods and time saving effects with the use of a PCR-based test.
The primary aim of both studies was to evaluate the concordance of [99mTc]tilmanocept with VBD, a mapping agent that is routinely used to identify SLNs.
After applying multiple background, intra- and inter-array effect corrections and signal extraction and probe summarisation techniques, we demonstrate the factors affecting the concordance of both magnitude and statistical significance of the transcriptomic effects between platforms.
To decide how many clusters were present in our data we calculated two indices, the Dunn index and the Calinski and Harabasz index, considering two to 10 clusters, but we also performed a hierarchical clustering to visualise the partition and study the concordance of both clustering methods.
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