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These observations indicate that cPAF disrupts both the cell cycle and the DNA repair mechanism, potentially increasing the risk of genomic instability.
To understand the possible mechanisms for STX140/2DG-mediated STX140/2DG-mediatede cell cycle state andeathhanism of cell death were assessed bothACS analysis.
Among the various mitogenic signaling pathways involved in SMC proliferation, the mTOR pathway regulates both the cell cycle and cell growth.
Therefore, it is surmised that PTEN protein localization may be dependent on both the cell cycle stage and the differentiation stage.
The p53 ambidextrously controlled the implementation of both the cell cycle arrest system and apoptosis induction system with employing the diversity of own dynamic behaviors.
In animal cells E2F, RB and MYB-related transcription factor form a complex known as DREAM, which represses both the cell cycle and cell differentiation-related genes [33].
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The present study paves the way for further research to better understand the role of the cyclin D1 pathway both at the cell cycle and molecular levels in stem cell-mediated glioma therapy.
Hence, we concluded that Pph3 is responsible for Rfa2 dephosphorylation both during the cell cycle and under HU treatment.
The partial antiestrogen, tamoxifen, and 'pure' antiestrogen, fulvestrant--first-line treatments for ER-positive patients--both modulate the cell cycle and reduce cyclin D1 and c- Myc levels [ 33].
In normal cells, serum withdrawal both arrests the cell cycle early in G1, also known as G0 and deactivates mTOR.
The temporal order of replication (replication timing) is linked to many basic cellular processes that are regulated both during the cell cycle and development.
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