Sentence examples for both the alterations from inspiring English sources

Both the alterations of the mTOR signalling cascade in AD brain and the outcome of the lymphocyte test were independent of the ApoE status of the patients.

Design and development of suitable multilayered systems for delaying corrosion advance in metals requires that both the alteration mechanisms of the metal and the behaviour and properties of the protective coatings be known.

In this connection, we have conducted several site-specific chemical modification studies with human lysozyme for the purpose of both the alteration of substrate specificity [ 12] and the clarification of the origin of carbohydrate recognition specificity [ 13].

Our observations in the acute post-injury phase may inspire potential neuroprotective therapeutic strategies, since both the alteration of ion current regulation and the activation of retinoid signalling can be pharmacologically modified.

The effects of exposure of perlecan to peroxynitrite was explored by examining both the alteration in the binding of antibodies that recognize specific epitopes on the protein core (domains I, III and V) and the HS chains, and specific oxidation products (3-nitroTyr and carbonyls) that may result from oxidative damage.

However, we lack an understanding of both the specific alterations in bone quality n steroid-induced osteoporosis as well as the mechanistic effects of these changes.

This report describes both the transcriptional alterations seen after transfection with MUC1 siRNA in human breast cancer cells and the effects on events such as apoptosis and proliferation.

They would have the advantage of providing personalized cancer treatments that account for both the genetic alterations and CSC status within a tumor, whereas protecting healthy tissues and cells.

Excessive oxygenation may be most intensively studied after resuscitation from cardiac arrest as both the vascular alterations and the ischemia and reperfusion injury are hypothesized to be hazardous [ 58].

In both systems, the alteration of RACK1 expression alters miRNA function and impairs the association of the miRNA complex with the translating ribosomes.

Both the spine alteration and BDNF transport blockade are tau-independent.