Sentence examples for both surrogate end points from inspiring English sources

This intervention study will run for at least 5 years and will be geared to find differences in both surrogate end points and hard end points.

These trials have used surrogate end points as the primary outcomes of interest.

These efficacy trials are using surrogate end points in an innovative Phase 2B trial design.

Furthermore, the use of surrogate end points in SCLC has not been explored.

The rationale for using IVUS-based surrogate end points in clinical trials is discussed in the present review.

However, it is not clear which potential surrogate end points are reliable and valid for studying pulmonary arterial hypertension.

Clinical trials often rely on echocardiographic measures of left ventricular size and function as surrogate end points.

Some studies, but not all, have demonstrated achievement of surrogate end points with lipid-lowering therapy in addition to LDL-C reductions.

For this reason, clinicians and health authorities have relied on so called surrogate end points to assess the efficacy of any therapeutic intervention for viral hepatitis.

It is found that for accelerated approval, the FDA relies upon surrogate end points that are not completely validated, but are reasonably likely to predict clinical benefit.

Hemodynamic, echocardiographic, neurohormone, and exercise measures hold some promise as potential surrogate end points for clinical trials of therapy for pulmonary arterial hypertension.