Sentence examples for both surface expression and from inspiring English sources

Furthermore, a ligand binding mutation within the ECD of mGluR5 (Y64A/thatA) that blocks ligand binding impairs both surface expression and dimerization of mGluR5 in neurons.

Both gp78/AMFR surface expression and AMF/PGI uptake are therefore significantly lower in normal immune cells relative to tumor cells.

Taken together, these results suggest that activity-dependent NL1 T739 phosphorylation is critical for both NL1 surface expression and NL1-mediated synaptic function.

Consistent with these studies, A457P mice are deficient in both NET surface expression and NE transport activity in native SNS and CNS noradrenergic nerve terminals, with NETP/P mice exhibiting near total loss of transport.

Additionally, the residual IgD+CD27+ had an altered phenotype both by cell surface expression and gene transcription profiling.

There was a significant increase in both TLR2 and TLR4 surface expression and mRNA on monocytes after adjustment for waist circumference.

Both proteins interact to regulate trafficking, surface expression, and activation of another potassium channel, KCNH3, in the cortex and in other parts of the central nervous system [ 17].

His219Ala reduced total and cell surface expression and cAMP production.

Mutant isoforms were characterized for cell surface expression and function.

However, identification of HSCs following expansion is complicated by changes in both surface marker expression and stem cell activity during the culture.

Only constructs which contained the TM of 5T4 exhibited both cell surface expression of CXCR4 and CXCL12 mediated chemotaxis.