Whether this reflects a causal pathway, where genetic or environmental factors influence the nature of the symptom or trajectory subtype experienced by an individual, or whether individuals with different subtypes differed in their susceptibility to different environmental factors, could not be determined.
Headache subtypes differed in the two age groups (Table 3).
The distribution of the molecular subtypes differed in the five regions, which is illustrated in Figure 1.
Although the distribution of molecular subtypes differed in women with high vs low MD, this was statistically non-significant (P=0.249), and further analyses revealed no association between the MD and Sorlie Perou subtypes as a whole, nor with individual subtypes.
Depending on the genetic etiology, the different genetic subtypes differ in terms of age of onset, pattern of hyperglycemia, response to treatment, and extra-pancreatic manifestations.
The study of such currents revealed that these two receptor subtypes differ in both affinity and gating properties.
This interesting aspect of tumor stroma interactions has not been extensively studied in vivo, although a recent paper notes that cancer-associated fibroblasts from different mammary tumor subtypes differ in their expression profiles (Tchou et al., 2012).
10.7554/eLife.06262.008 Figure 4. Golgi cell subtypes differ in their sensitivity to iNC input and have different intrinsic properties.
These intrinsic subtypes differ in incidence by race and menopausal status [ 7] and show differences in risk factors [ 8], outcomes [ 7, 9], and responsiveness to chemotherapy [ 10].
The COP coats of peri-Golgi vesicles appear as homogeneous or 'spiky' subtypes, whereas it remains unclear, if 'spiky coats' and 'homogeneous coats' represent distinct subtypes differing in genesis and protein composition, or if they are COP coats at different stages of coating/uncoating (Bouchet-Marquis et al. 2008) (see Fig. 3).
