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In comparison, 16 (53 %) of the seropositive patients were treated with corticosteroids, with 2 having prednisone doses ≥10 mg/day at both study start and end (p = 0.086).
Infections occurred in 14 (82 %) of 17 patients taking prednisone ≥10 mg/day at both study start and end, compared with 62 (35 %) of 122 patients without sustained high-dose prednisone or without corticosteroids (p < 0.001).
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The average study duration was calculated from study start and study completion dates.
Prohibited medication prior to study start and during the study were as follows.
Both studies started by sequencing genes and detecting SNPs to elucidate population structure.
Baseline characteristics according to randomization group: at birth, at GH start and at study start.
Recruitment for this study started February 2011 and continued until November 2011.
This ongoing study started from January 2011 and will complete in March 2015.
Study participants consented to participation prior to study start.
Blocks were defined by study start dates (n = 3).
was granted prior to study start.
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