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In both study arms, the majority (approximately two thirds) of the patients were female.
In both study arms, the most common reported problem was that additions to chemotherapy support medication were unclear to staff.
From weeks 12 through 16, after discontinuation of metronidazole in both study arms, the improvement noted in the first 12 weeks receded in subjects who received only placebo compared with those subjects receiving only anti-inflammatory dose doxycycline.
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In the current study, we measured a bone loss of 0.5 mm in both study arms in the period between the implant placement and the baseline radiographs.
However, the absolute rate of intensification of medications to control A1c increased in both study arms at the end of the study by a modest amount (∼6%).
Comparison of the eGFR of all patients (both study arms) for the first 10 days after starting on the most frequently used beta-lactam antibiotics showed that the slowest recovery of renal function was observed in patients on piperacillin/tazobactam as compared with patients on meropenem or cefuroxim (figure 1).
Furthermore, scoring of the prognosis of each patient in both study arms using the Cox regression model and estimation of the risk for each patient were carried out with the selected covariates.
In addition, HbA1c levels of the patients in both study arms of the pilot RCT were mostly already prioritised at baseline and adjusted at low levels.
This effect is expected to be equal in both study arms in the primary care trial.
In our study, the median time for patients to meet criteria for clinical stability was 4 days in both study arms, but the time to actual switch was 5 days in both study arms.
The mean fluoride content was 0.41 ppm ± 0.38 ppm for both study arms, and the baseline levels for NaF and amine fluoride were statistically not different (Table 1).
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