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The response rate for both studies was lower than anticipated, particularly so for MANCAS2.
The value for moderate COPD in both studies was lower than that of our present study, while the value for severe and very severe COPD in both studies was higher than that of our present study.
In the studies by Douillard et al (2002) and Carmichael et al (2002), the incidence of grade 3/4 neutropenia in UFT-treated patients (3% of patients in both studies) was lower than that observed in the present study (25% of patients).
Similar(57)
Nevertheless, the point estimates in both studies are lower than those reported by other authors [ 20- 24].
The incidence of injection-site reactions in both of these studies was lower than the 30.8% reported for the 91 adalimumab monotherapy patients (40 mg every other week) in the CHANGE study, 14 possibly related to the immunosuppressive effects of concomitant MTX in the current study and in some of the patients in the HARMONY study.
Recruitment into non-inferiority randomised controlled studies was lower than that into step-up randomised studies (p = 0.06).
Both another study from Sweden and a Norwegian study report an increased risk of death., The risk of death in those studies was lower compared with our study.
The prevalence of bacterial contamination in these studies was lower than our investigation.
The antithrombin levels in both the DIC and ACOTS patients observed in the present and previous studies were lower than those in the control subjects [ 17, 18].
Overall, the key outcomes of the included studies were lower limb muscle strength, flexibility, balance, and depressive symptoms.
Participation in population-based health studies is lower among individuals with alcohol problems [ 58].
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