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The kind of night shift work and secondary post-hoc analyses of both studies may explain the different findings.
Different solubilisation conditions (detergent concentration, buffer system), and finally different physical properties of a ligand-binding assays used in both studies may explain the slightly lower affinity of the VGSCs observed here.
15 It is possible that the presence of diabetes, more severe CKD (median eGFR 33 (27 46) vs 51 (44 58) in Bowman's study) or relatively small numbers in both studies may explain the difference between these two sets of results.
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Absence of other tocopherols in these latter studies may explain the conflicting results.
The lack of comprehensive, wide scale studies may explain, at least partially, the controversy concerning PRF impact and mechanisms involved.
Alternatively, differences in methodologies between studies may explain findings.
Varying degree of misclassification of exposure across the studies may explain some of the heterogeneity.
A number of differences between the two studies may explain the different findings.
The choice of subjects and the varying methodologies of these studies may explain the discrepancies.
The use of different status biomarkers in these studies may explain partly the mixed results of different studies [ 39].
In general there is considerable heterogeneity between the studies and between subgroups; methodological diversity between studies may explain the heterogeneity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com