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This suggests that saturation mutagenesis can be more selectively guided for evolution towards either natural or non-natural substrates, using both structural and sequence information.
appear to be homoplasious in origin, demonstrating analogous functions but lacking convincing evidence of both structural and sequence homology.
In order to clarify this discrepancy, we here present a proper classification of the p115 ARM-motifs by combining both structural and sequence information.
Both MV and DISPLAR use both structural and sequence information in predicting DNA-binding sites.
b Type; descriptor based on structural (str), sequence (seq) or both structural and sequence (mix) properties of the hairpin.
Furthermore, the neurotoxin's HCRn domain was found to exhibit both structural and sequence similarity to eukaryotic collagen jelly-roll domains.
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Because the MHC is subject to extensive variation, both structural and sequence-wise, it is not readily amenable to study in whole genome shotgun sequence such as the recently published gorilla genome.
The results of surface analysis suggest that AG73-G3- PPG 5 can be stably adsorbed onto PLA films via hydrophobic interaction at the (PPG 5 region, and form an extracellular matrix-like layer composed of both structural and biosignalling sequences.
The neuroimaging protocol comprises both structural and functional sequences and lasts approximately 50 minutes.
The partial conformation allows users to specify both the structural and sequence constraints for each state.
The results suggest that flanking regions are relevant for linear motif mediated interactions, both at the structural and sequence level.
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