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Only those terms appearing between 2 and 40 times, maximizing both specificity and coverage, were retained.
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The optimization is carried out by optimizing output information granules produced by the granular model by considering a product of the essential criteria describing information granules, namely specificity and coverage.
The algorithm was proven to outperform existing methods and to be suitable for function prediction of single proteins due to its high degree of sensitivity, specificity and coverage.
Using the RDP classifier and the BLAST program, Baker et al. (2003) and Huws et al. (2007) have investigated the species specificity and coverage spectrum of the known primers.
Table 1 shows sensitivity, specificity, and coverage metrics for the custom multiplexes at different MAF thresholds.
Five non-overlapping probes showing the best specificity and coverage were then selected for each genus.
The Biological Process tree was expanded to the fourth tier in the hierarchy as a balance between specificity and coverage.
The enrichment analysis was performed on the third GO level, because this gave the best compromise of specificity and coverage of the gene list.
The specificity and coverage of the resultant alignments are tested against the orthologous groups defined in the eggNOG database v3.0 [ 42].
These data, the wheat LCG assembly and the homology to the complete barley gene space provide a novel and unique reference for RNA-profiling studies, allowing a high specificity and coverage of the transcriptome.
The versatility of PMOS is derived from its ability to achieve both high specificity and high coverage in a very small library.
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