The present study was conducted to test accuracy and reliability of GOX and GDH based BGMs at simulated and true high altitude.
[4] Furthermore, Öberg and Östenson tested four GDH and one GOX based BGM at simulated and true high altitude up to 4500 and 5895 m respectively.
The purpose of this study was to investigate whether modern GDH or GOX based BGMs are reliable under simulated and true high altitude conditions.
We then calculated ∑ i =1 sim i − true i ), where sim i and true i denote the simulated and true proportions of alleles private to geographic combination i, respectively.
The procedures are described and evaluated with respect to false-positive (i.e., DIF is detected when not simulated) and true-positive (i.e., DIF is detected when simulated) detection rates under several study conditions.
Posterior samples of gene trees, for both simulated and real alignments, were downloaded together with the 'true' gene trees used to simulate alignments from the dryad data repository (doi 10.5061/dryad.pv6df) provided by Szöllősi et al.
Prediction accuracies were defined by the correlation of the true (simulated) and estimated paternal additive genetic effects for each underlying trait.
The major limitations of this study are that no detectors were simulated and the source was simulated as a true pencil beam.
The greatest degree of disparity between simulated read cluster heterozygosity and true simulated heterozygosity occurred at low mismatch thresholds.
