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MsrR of S. aureus as well as Psr of Enterococcus faecalis were both shown to increase virulence in the model host Caenorhabditis elegans [ 9, 10].
The levels of endogenous and exogenous EBNA1 proteins expressed in the same cells were both shown to increase following an 8-hour treatment with 400 nM DXR (Fig. 4E).
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However, Mel-18 and Bmi-1 have both been shown to increase proliferation and survival of cancer cells [51].
Both were shown to increase response rates to between 45 and 75%, but these strategies are not feasible in routine medical practice.
Indeed, caloric restriction and alternate-day fasting have both been shown to increase longevity [ 6] and reduce metabolic risk factors [ 7].
The mutants which disrupt function of the B. pseudomallei Resistance-Nodulation-Cell Division (RND) superfamily BpeAB-OprA [ 23] and Amr-OprA [ 24] efflux systems have both been shown to increase the susceptibility of this organism to aminoglycosides.
Rifampicin and the herbal supplement St. John's wort have both been shown to increase the clearance of the oral contraceptives ethinylestradiol and norethindrone (Barditch-Crovo et al. 1999; Hall et al. 2003).
More recently, both peptides were shown to increase the synthesis and release of anti-inflammatory molecules like IL-10 and the IL-1Rα (IL-1 receptor antagonist), leading to a suppression of inflammatory responses (Delgado et al., 1999c).
In both cases, cGKII was shown to increase the cell surface expression [29].
Both agents have been shown to increase counterregulatory responses.
Both strategies have been shown to increase survival rates since 2003 [ 24, 25].
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CEO of Professional Science Editing for Scientists @ prosciediting.com