Here we report the design of a peptidergic compound, Ac-DGGLAG-NH2, called P21, when administered peripherally, enhanced learning as well as both short-term and spatial reference memories of normal adult C57Bl6 mice.
Importantly, both short-term and long-term spatial habituation were disrupted by hippocampal lesions (Sanderson et al., 2009b).
Although the battery of learning tests used is by no means exhaustive, our aim was to assess both short-term and long-term memory, in both spatial and non-spatial domains.
Unlike protective sequestration, flight has the potential to increase mixing in the short term, and across spatial regions (even if it ultimately removes individuals from circulation locally).
This game helps build short term memory and spatial sense.
These data illustrate that vaccinated mice retain spatial information as well as non-transgenic mice, and significantly better than non-vaccinated 3xTg-AD mice do, i.e. both short-term (1.5 hr) and long-term (24 hr) spatial reference memory were improved in immunized animals.
The human perceives the information about the environment from multiple sensory complex cues, creates and maintains spatial representations in short-term and long-term spatial memory and applies the created spatial representations to direct navigational behavior [31].
Results are consistent with an extended number processing network and suggest that important processing nodes of this network are phonological processing, verbal knowledge, visuo-spatial short-term and working memory, spatial ability and general executive functioning.
This paradigm gives the opportunity to dissociate poor performance along these measures (cue approach acquisition, spatial acquisition, and short-term and long-term spatial memory), which can allow accurate study of animal deficit.
Cambridge Neuropsychological Test Battery (CANTAB) Spatial span length: (number of items that can be held in short term memory), Spatial span total errors (the number of times an incorrect item is selected), Spatial span usage errors; the number of times an item is selected out of sequence.
Attention here is also associated with short-term memory and spatial orientation as well.
