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This implies a pleiotropic locus containing both shared and distinct causal variants for different phenotypes39 where the psoriasis, IBD and PBC SNPs likely tag the same causal variant, but with an independent causal variant for asthma.
We have shown that hEXO1 and hFEN1 exhibit both shared and distinct biochemical activities on telomeric substrates.
The above data suggested that there were both shared and distinct features of SF and SC fibrocytes.
Hypomorphic dcl1 mutants and null hyl1, hst, and hen1 mutants reveal both shared and distinct developmental defects that may represent misexecution of developmental transitions [24].
Since the two NF-κB pathways employ both shared and distinct components, the role of each activation pathway in B cells remains to be elucidated [18].
Over the years, the importance of genetic factors in psychiatric disorders has become increasingly apparent, with overall heritability rates for depressive disorders, anxiety disorders, and suicide ranging between 30 50% [7] [11], involving both shared and distinct genetic vulnerabilities [12] [15].
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Through theoretical and numerical analyses, we demonstrate that our method provides accurate covariance estimates, thereby enabling researchers to dissect both the shared and distinct genetic architecture across traits to better understand their etiologies.
Han, B. et al. Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity 1.
Furthermore, complex DC networks consist of many DC subsets with shared and distinct functions.
Stresses such as drought, cold and salinity have shared and distinct signaling pathways, some of which are ABA-dependent [ 18].
DAF-16 and HSF-1 have shared and distinct regulation of downstream genes, especially those of the chaperone class.
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both shared and personal
both shared and opposite
both conserved and distinct
both shared and private
both shared and polymorphic
both shared and non-shared
both shared and vertical
both shared and nonshared
both shared and drug-specific
both shared and individual
both shared and idiosyncratic
both shared and non‐shared
both repeated and distinct
both shared and endometrial
both shared and stimulus-specific
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