Sentence examples for both sets of target from inspiring English sources

The apo-ER/apo-RARα1 axis regulates genes in both a positive and a negative manner to support cell division; both sets of target genes were enriched for associated chromatin sites of RAR binding, suggesting that RARα1 must act on these target genes by direct as well as indirect mechanisms.

We found a striking enrichment of both sets of putative FOXP2 targets among genes differentially expressed between PFO and PT, but not between 17 and 19 GW (Figure 7C,D and File S1).

For those identified in both datasets, the corresponding sets of target genes were analyzed separately.

In particular, the oncogenic potential of the carboxyl-terminal dimerization and DNA binding domain of Myc2 is substantially lower than that of Myc1 suggesting that both Myc paralogs regulate different sets of target genes, although the amino acid sequences of the basic regions and their DNA binding affinities are very similar (cf. Fig. 4D).

As a result, the significance of the Mann–Whitney test comparing the expression of targets in both sets of samples may be diminished, causing the loss of some significant targets.

For example, targets predicted for let-7a are shifted toward better free energies than are those predicted for both sets of controls (Figure 1B), whereas targets predicted for miR-17-5p and its controls show similar energy distributions (Figure 1C).

However, whether these sets of target genes can mediate the glucocorticoid response will require further study.

These two TF complexes associate with two distinct sets of target genes.

Additionally, proteomic studies showed that SUMO1 and SUMO2/3 have partially overlapping sets of target proteins.

This suggests that NF-κB and GR have overlapping sets of target sites.

This may lead to different sets of target genes regulated by the same TF.