Sentence examples for both sequence mutation and from inspiring English sources
An alteration frequency score for each gene was calculated, based on the 84 GBM cases with both sequence mutation and copy number data (hypermutators excluded).
Both sequence mutation and alteration in methylation pattern were detected.
Both the ATF sequence mutations and the methylation of the promoter are oncogenic [ 9, 10, 13, 17], suggesting that this sequence variant associated with methylation could also be oncogenic.
We investigated sequence mutations and expression of DCC in primary gastric cancers.
Sanger-sequencing confirmed both the mutation and wild type sequences.
To gain a global view of genomic alterations occurring in glioblastoma, we restricted our analysis to the 91 TCGA GBM cases, for which both copy number and sequence mutation data were available.
This suggests that when both sequencing and mutation analysis are 100% successful, 8% of patients (57 minus 49) would receive anti-EGFR therapy in vain when only exon 2 of KRAS would have been assayed.
Usually, slower sequence mutation results in higher sequence conservation and faster sequence mutation results in lower sequence conservation.
Both CREBBP and EP300 sequence mutations have been reported in solid tumors and, more recently, also in hematological malignancies, whereas rare EP300 mutations have been detected in some ALL cell lines [ 29, 31].
They include all sources of protein variation, and heres a list: sequence mutations, alternative splicing, and post-translational modifications (PTMs).
To show the importance of the KL interactions, a control molecule (T4*) was prepared, in which a pair of KL interaction was disrupted by sequence mutation.
