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Numerous ROs have been identified and characterized from bacteria, thereby enriching the available information on their diversity in terms of both sequence and function (Habe and Omori 2003; Iwai et al. 2010, 2011; Chakraborty et al. 2012).
Norwalk virus nonstructural protein p22 contains a YXΦESDG motif that mimics a di-acidic ER export signal in both sequence and function.
Among the 42,682 proteins obtained, there were 14,732 proteins with both sequence and function information, constituting the benchmark dataset.
Cdc45 is crucial for DNA replication initiation and elongation and is conserved among eukaryotes in both sequence and function.
The combined method was tested by using alignment results from MAS (both sequence and function based) as input.
Separating multimodular proteins into module units makes it possible to generate protein groups related by both sequence and function, avoiding mixing of unrelated sequences.
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This affects both protein sequence and function prediction, so these considerations demand an easy way to assess the genetic code used on a sequenced fragment or assembled contig.
Nevertheless, because GA does not seem to act directly on the PrP conversion process and because it is active against both yeast and ovine prions which are not related both in term of sequence and function, we believe this drug acts on common prion controlling mechanisms conserved in eukaryotes.
The antiprion activity of both drugs was evidenced with different, unrelated prion proteins, both in terms of sequence and function, and in different organisms ranging from yeast to mammals (Bach et al, 2003; Tribouillard et al, 2006; Tribouillard-Tanvier et al, 2008a).
His research focuses on genome sequence and function in both humans and related primate, mammalian and vertebrate species.
Ameres, S. L. & Zamore, P. D. Diversifying microRNA sequence and function.
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both size and function
both fun and function
both design and function
both fit and function
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both sequence and location
both sequence and brain
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both development and function
both sequence and phenotypic
both sequence and orientation
both sequence and taxon
both morphology and function
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