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With 96-well throughput, cells with similar sfGFP output to that seen with VB2 were identified by both random and selective screening (Fig. 4a, b).
The -secure property of -degree polynomial is exploited to achieve high resilience against both random and selective node capture.
Duplicated genes are often lost by both random and selective processes in a short time, but that also means there is a chance to encounter multiple gene copies in a specific lineage [ 22].
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Analysis by PCR of the genomic DNA from the highest-performing sfGFP strains from the random and selective screens (GB2 and GH3, respectively) showed that neither had replicated either of the two SCRaMbLE events identified by sequence analysis of VB2, and so each had achieved increased fluorescence via different chromosome rearrangements (Supplementary Fig. 14).
Invasive species can harbor substantial genetic variation among populations, owing to random and selective forces (Bossdorf et al. 2005; Dlugosch and Parker 2008).
Interestingly, in our RNA-seq data either the miRNA or the miRNA* (including miRNA**) arms were expressed at many miRNA loci (Additional file 5 Figure S2), suggesting a non-random and selective expression of the two different miRNA arms.
The slogan memorized by generations of students of natural selection is random mutation and selective retention.
It accomplishes this through means that extend beyond random variation and selective filtering.
Only it turns out some of those invitations went to people they shouldn't have -- and to people who didn't even mean to apply for the Glass program to begin with -- sparking some speculation that Google's selection process was more random, and less selective, than the company had implied.
CNV represents a major form of genetic variation within the P. falciparum genome; the distribution of gene features indicates the involvement of highly non-random mutational and selective processes.
We judged a low risk of bias for this trial for random sequence generation and selective reporting.
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