Sentence examples for both protein expression and from inspiring English sources

As the GR-α and GR-β isoforms originate from alternative splicing of the same gene, the only accurate way of specifically quantifying the GR-β isoform is using qPCR, which precludes information about both protein expression and function.

A method that permitted this to be done simultaneously would be convenient and would provide information on both protein expression and modification.

In human cardiomyocytes isolated from the left ventricle of patients with end-stage heart failure, gene transfer of SERCA2a resulted in an increase in both protein expression and pump activity, and induced a faster contraction velocity and enhanced relaxation velocity, thereby restoring these parameters to levels observed in nonfailing hearts [17].

Cyclin D1 was evaluated concerning both protein expression and regional amplification of the CCND1 locus.

Studies of both protein expression and function are required to identify if these proteins may represent novel therapeutic targets.

Accurate interpretation of modification data thus requires estimates of both protein expression and levels of specific modifications.

Modified peptides should also be filtered out, because their abundances might combine changes both in protein expression and in differential modifications (Wu et al. 2011).

Optimization of linkers has been shown to improve both protein expression yield and biological activity [ 40].

Akt1 siRNA reduced both Akt protein expression and phosphorylation, indicating a greater preponderance of Akt1 in TSC2−/−ASM cells.

Interestingly, COMT/2ME exerts a dual effect on PRs as it inhibits both total protein expression and nuclear localization.

Because IL-1β/IL-18 or TNFα blockade inhibits both IκBζ protein expression and IFNγ production in KG-1 cells, we hypothesized that IκBζ positively regulates IFNγ production.