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Furthermore, association studies have identified both promoter and coding region polymorphisms in the TGFβ1 gene that associate with increased risk for COPD [ 46- 48].
We have observed that RSC is important to mediate nucleosome reorganization at both promoter and coding region of osmo-responsive genes; however, we detect only the recruitment of RSC at the coding regions of stress genes.
In contrast, whole genome microarray experiments in synthetic complete (SC) medium reported that Mediator associates with many genes at both promoter and coding regions.
In contrast to our results, other whole genome microarray experiments reported that Mediator associates with many genes at both promoter and coding regions in S. cerevisiae [11] and S. pombe [12] cells grown under non-stressed conditions (synthetic complete medium).
We focused on both promoter and coding regions to understand the silence of 1Ay alleles.
For this purpose, a genomic clone containing both promoter and coding regions of ETR1 was used.
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A previous study suggested that genes that are up-regulated in nitrogen depletion are clustered and associated with nucleosome eviction in both promoters and coding regions [ 26].
Polymorphisms in both the promoter and coding region of the MBL gene (MBL2) have been shown to influence the concentration and function of expressed MBL, resulting in deficiency [9].
Furthermore, a 4.2 kb fragment including the promoter and coding region of OsWOX3B was cloned into pCAMBIA1301 and transferred into HMK.
Complementation of the mutation was achieved using a 7.6-kb genomic DNA fragment containing the promoter and coding region of GLR3.1.
None of these studies focused on SNPs present in the promoter and coding region of GLUT4.
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