Enhanced development of presynaptic and postsynaptic components of noradrenergic synapses as a result of neonatal hyperthyroidism.
Phorbol esters increased the amplitude of the postsynaptic components of the field potential, including the excitatory post-synaptic field potential (fEPSP) and the population spike following electric stimulation of parallel fibers.
GABAA receptors (GABAARs) are the essential functional postsynaptic components of GABAergic synapses (Schofield et al., 1987; Sieghart, 2006; Farrant & Kaila, 2007).
To determine whether expression of GABAA receptors (GABAARs) themselves – the essential functional postsynaptic components of GABAergic synapses – can be sufficient to initiate formation of synaptic contacts, a novel co-culture system was devised.
In view of the functional co-reliance of presynaptic and postsynaptic components of mature synapses, it is perhaps not surprising that the degeneration process does not involve the synaptic elements separating and going their separate ways.
Our model has some similarities with the triplet-STDP model introduced in Pfister and Gerstner (2006), however note that the triplet model does not distinguish between pre- and postsynaptic components of expression.
A small protrusion of the dendritic membrane that represents the postsynaptic component of the majority of the excitatory synapses in the CNS.
Since MB-V3 are postsynaptic to Kenyon cells, this could reflect a postsynaptic component of LTM.
Nonetheless PPR and time constant measurements in whole cell recordings suggested a postsynaptic component of Roscovitine LTP; It is known PPR is not a total convincing protocol to evaluate presynaptic effects when a postsynaptic component is involved.
In this conditions, HFS did not induce long-term plasticity (pre-HFS=98.18412±1.192 versus post-HFS=84.247±8.01, t5=1.628 P=0.1644, t test), showing that the PKA signaling pathway is associated with to the postsynaptic component of Roscovitine-induced LTP.
