Sentence examples for both pathways to be from inspiring English sources

If Noggin inhibits inhibits both Smad1/5/8 and Smad2 activity, we expect the downstream gene targets of both pathways to be silenced by Noggin treatment.

Some pervasive transcripts seem to be immune enough to both surveillance pathways to be detectable in wild-type cells and are called SUTs (stable unannotated transcripts; Xu et al., 2009).

There are 2 main pathways that result in apoptosis, the intrinsic (mitochondrial) and extrinsic (death receptor) pathways; it is possible for both the intrinsic and extrinsic pathways to be activated simultaneously within tissues [ 28].

Remarkably, the present study showed that combined suppression of the MAPK and PI3K/Akt pathways synergistically promoted cell apoptosis, suggesting that both pathways need to be removed to induce melanoma cell death.

Although two possible pathways, adenoma carcinoma or de novo cancer sequence, have been proposed, the relative importance of both pathways to cancer has been rarely addressed.

To further investigate the two pathways for H3 + formation under identical conditions, an organic molecule capable of reacting via both pathways has to be studied.

The possible interplay between both pathways remains to be elucidated.

This inhibitory crosstalk between both pathways appears to be unidirectional, since estradiol did not alter the transcript levels of an AHR target gene.

Both pathways appear to be regulated in a very tight manner during embryogenesis.

To what extent these differences influence the metastatic capacity of both pathways remains to be elucidated.

In the absence of CO2 stimulation, both pathways appear to be inhibited in L3s by an analogue of the "insect juvenile hormone", which is implicated in the regulation of development in insects [ 3- 6].