Sentence examples for both pathways need to from inspiring English sources
Remarkably, the present study showed that combined suppression of the MAPK and PI3K/Akt pathways synergistically promoted cell apoptosis, suggesting that both pathways need to be removed to induce melanoma cell death.
The Arf/p53/p21 and p16/pRb pathways therefore cooperatively regulate induction of senescence, and usually both of these pathways need to be intact for maintaining the senescent state [ 6, 7].
Treatment of IR in morbid obesity and T2D is more complex because both inflammatory and neuroendocrine pathways need to be targeted.
We suggest that to achieve a full H-RAS transformation of the late HF1 cells both the PI3K-PKB and H-RAS pathways need to be intact.
We conclude that all four pathways fail to protect the mutually beneficial UK EU biotechnology relationship and that alternative pathways need to be explored.
As such, to obtain a significant p-value, larger pathways need to accumulate a larger number of gene amplifications or deletions.
[33] To gain more insights on the anticancer mechanisms of combination therapy, other non-apoptotic signaling pathways need to be investigated and these studies are in progress.
However, these pathways need to be further elucidated to identify the causation.
Third, resources and care pathways need to be optimised to accommodate detection and follow-up.
