Sentence examples for both pathways have shown from inspiring English sources

Antibodies directed to proteins in both pathways have shown significant activity especially in combination with chemotherapy, and studies in the adjuvant setting are in progress.

Molecules targeting DNA repair pathways have shown great potential to sensitize tumor cells to both chemo- and radiotherapy and increase their cytotoxicity [ 5].

Encouragingly, small molecule inhibitors of these pathways have shown promise in clinical trials or are approved for clinical use.

Anti-cancer drugs targeted to specific oncogenic pathways have shown promising therapeutic results in the past few years; however, drug resistance remains an important obstacle for these therapies.

Among 19 receptor tyrosine-kinase related pathways, three pathways have shown pathway level difference with two mutational events (Table 3).

Indeed, genetic variations in these pathways have shown to modify the risk for BC [ 29].

Studies of these two pathways have shown that CRC is a genetically heterogeneous disease [ 4].

ERK pathway is known to prevent cell death, whereas the JNK/SAPK and p38 pathways have shown proapoptotic actions.

Pathways have shown success in bringing about change in patient management, depending on context and implementation [ 12, 13].

Excised enzymes from natural product biosynthetic pathways have shown great promise in chemoenzymatic synthesis providing diverse natural product analogs.

Many molecular pathways are implicated in carcinogenesis, and agents targeting these pathways have shown some efficacy in BTC cell lines [ 31, 32].