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Both pathways can be inhibited by suramin.
Besides the described role in proliferation and migration, both pathways can be involved in HPC differentiation.
Both pathways can be activated by a variety of inputs and mechanisms.
Both pathways can be easily studied in the same hippocampal slice, an approach we employed to examine the SC and TA pathways in DISC1tr mice.
Although no components of the Drosophila Toll and IMD pathways have been identified as virus sensors, both pathways can be activated by viruses, and their activation contributes to the restriction of viral replication.
If it is assumed that an average of one midge accompanies each large animal being transported, both pathways can be combined to yield a single probability of introduction (Fig. 7), to which infectious hosts appear to be the main contributors.
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The replicative p53-p21-pRB p53-p21-pRB p53-p21-pRBe stress-induced pathway pathway, played a moratherorthan role in the senescence of NPCs in an in vivo condition, although there is a situation in which both the pathways can be activated simultaneously.
Since the prevailing models of BAK activation suggest that each are equally possible, both activation pathways can be combined in a unified model (figure 7A and 7B).
Furthermore, depending on the nature of the cell signals, both apoptotic pathways can be either initiated or repressed.
Although the extrinsic and the intrinsic apoptosis pathways are activated by different stimuli, both these pathways can be regulated by specific miRNAs.
The proposed dependence of the regulation of autophagy on Wnt and Hh signalling is of particular interest, since both morphogen signalling pathways can be considered as master regulators of liver zonation.
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