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Both overall levels of replication and breadth of tissue tropism may be positively correlated with virulence.
We show that loss of core pathway function and also reduction of RhoGEF2 and RhoA activity give a similar phenotype to blocking endocytosis in this tissue, resulting in increases in both overall levels of and the stable fraction of E-cad at junctions, and a delay in cell intercalation.
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Although we used self reported sport participation and school PE grade, these have both been associated with overall levels of physical activity in adolescents [16], [17] and with physical activity in later life [19], suggesting that our outcome measures are likely to reflect overall levels of physical activity.
Thus, as discussed above (for example, see [ 42- 44]), expression and shedding activities can both independently contribute to overall levels of soluble adhesion molecules in circulation.
Once again there was no overall difference between the exploration levels of the two groups (F< 1; Fig. 5B), and both groups showed lower overall levels of exploration for the familiar objects than for the 'novel + novel object' condition in Trials 1 6 of Experiment 1b (effect of condition, F1,20 = 63.38, P< 0.001).
The dog walkers had higher overall levels of both moderate and vigorous physical activity than the other subjects, and they were more likely to take part in other leisure-time physical activities like sports and gardening.
The overall levels of both RNAIII (Fig. 1) and extracellular proteases (Fig. 8) were comparable between UAMS-1625 and the other USA300 isolates, and the impact of mutating sarA on the production of extracellular proteases was comparable in all strains other than RN6390 (Fig. 8).
The overall levels of both EGR2 and MeCP2 showed gradual, coordinated increases in postnatal brain with age (Fig. 3B).
In addition, we assessed whether the rate of decline was similar for all seven countries and both sexes, despite differences in overall levels of stomach mortality rates.
During both development and adult life, overall levels of NGF determine a balance between cell proliferation and apoptosis of target cells [ 3].
In addition to utrophin up-regulation, dystrophin expression is up-regulated by 4-fold in WT DTG muscle thereby increasing overall levels of both DGC and UGC (Fig. 6).
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