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These nanoscale devices interact with biomolecules both on the surface of and inside cells with unprecedented efficiency, which may improve disease diagnosis and treatment drastically [16, 17].
Detection of viral RNA in the supernatant from the first two pollen washings (washings with Trizol or PBS and SDS solutions) and then pollen homogenate after a fourth washing suggests that either the virus particles were present both on the surface of pollen grains as well as inside the pollen grains or that they were tightly bound to the pollen exine.
However, 10 out of 18 (55.6%) VHL+/− and 4 out of 4 (100%) EAF2−/−VHL+/− mice displayed large discrete lesions visible both on the surface of the liver and within the liver parenchyma (Fig. 2a).
The EQCM and UV vis studies indicated that the polymer is formed both on the surface of the substrate and in the bulk of the polymerization solution.
The used three-dimensional (3D) model considers heat conduction and accumulation in the solid phase (Fourier equation) and mass and heat balances both on the surface of the catalyst and in the gas phase.
Therefore, the good rate capability is not only owing to the higher conductivity of the NiCo2S4, but also due to the highly porous structure of the interconnected NiMoO4 nanosheets filled both on the surface of the NiCo2S4 nanotubes as well as the spaces between them, which further increases the accessibility of the microscopic area.
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As it can be seen in Figure 1a, a designed platform comprises the ACPNs, which are trapped in a liposomal shell, and folate as TL and TAT as CPP which are both positioned on the surface of the liposome.
Our results showing that TLR2 is both upregulated on the surface of lung-migrating inflammatory monocytes and contributes to the production of type 1 IFN in MHV-68-infected mice are consistent with this report.
This acidic pentapeptide together with the DYDYQ sequence (20, 22, 23) are both located on the surface of the factor Va molecule (41) and are conserved among species, attesting to their physiological significance.
CS forms colloidal particles and entraps bioactive molecules both inside and on the surface of such particles.
During the reduction of 4-nitrophenol by NaBH4, the electron transfer from BH4 − to 4-nitrophenol occurred when both are adsorbed on the surface of the catalyst.
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