There are several genetic defects that cause chronic granulomatous disease, all of which impair the ability of phagocytes to make hydrogen peroxide.
Group II contains proteins the mutations of which impair the photosystems, while group I contains proteins the mutations of which do not affect photosystems.
Mental health disorders are characterised by emotional distress and impaired cognitive function, which may lead to workplace accidents, aggression, substance abuse, eating disorders, anxiety, and depression, all of which impair one's ability to work.
Putative functional alleles were then genotyped in a large Swedish cohort, which ultimately yielded two independent association signals within both IKBKE (one of which impairs the binding motif of SF1, thus influencing its transcriptional regulatory function) and IFIH1.
Since 1993, Mrs. Gore has endured a heart attack, brain surgery to remove a blood clot, and two strokes, one of which impaired her vision.
The most obvious reason is that there is tremendous variation in the sensory, physical and functional states of which "impaired" or "disabled" people are capable.
Impaired response inhibition is a behavioral trait of which impaired satiety may be one manifestation.
Similarly, we have identified Foxd3, a Klf4-specific target (that is, not regulated by Klf5), suppression of which impairs self-renewal (data not shown).
Spinal cord injury (SCI) commonly results not only in motor paralysis but also in the emergence of neuropathic pain (NeuP), both of which can impair the quality of life for patients with SCI.
For example, we did not assess neuropsychological functioning or medical illnesses, both of which may impair functioning or augment distress, nor did we assess personality disorders, although the value of assessment of these in younger adults is debatable, especially in those aged 12 to 15 years or so.
