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Both of these tissue combinations had 20 processes in common, which were closely followed by the kidney medulla-lung tissue combination with 18 commonly affected processes.
Accordingly, it is expected that functional γ-secretase complexes in both of these tissue culture models contain predominantly or solely the exogenously expressed PSEN mutants.
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The size of the mRNA in both of these tissues was estimated to be approximately 2.1 kb, furthermore both tissues appear to have the same transcription initiation site as determined by nuclease protection.
As a result, the epiblast becomes positioned toward the distal part of the egg cylinder, the trophectoderm-derived extra-embryonic ectoderm (ExE) locates in the proximal part, and both of these tissues become enveloped by primitive endoderm-derived visceral endoderm (VE).
We have further documented that pressure-mediated delivery of antisense ODN can functionally inhibit target gene expression in both of these tissues in a sequence-specific manner at the mRNA and protein levels.
Additionally, titration or competition appears to occur specifically against the neural enhancer not the limb enhancer, even though Evx2 promoter activity is prominent in both of these tissues.
The variation in appearance both of these tissues and of the liver biopsies is discussed.
Both of these tissues are characterised by extensive cellular differentiation and wall deposition.
This would be in accordance with the common function of BRCA1 as a tumour suppressor in both of these tissues.
Among them, TLR and NLR signalling pathways are commonly found in the URGs of both of these tissues.
Both of these tissues show higher divergence within rat non-homologous tissue comparisons as well as between homologous rat-mouse comparisons.
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