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Both of these modifications require the RING domain-containing protein Pex10p in vivo, but the actual role this protein plays in the ubiquitination of Pex5p has so far, remained enigmatic.
Both of these modifications improved accuracy while reducing the FNR; however, the FNR still remained relatively high.
Both of these modifications have a crucial role in the folding, acquisition of the functional capacity, and later appropriate sorting of the SI molecules to the BBM [5].
The LfcinB-derived hexamer was originally studied with a free N-terminus and an amidated C-terminus, and the Combi peptide was originally studied with both of these modifications.
Our analysis may include both of these modifications.
Both of these modifications activate p53 transcriptional activity and induce cell apoptosis or senescence [ 18, 49].
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It will be interesting to determine the exact mechanistic contributions of these modifications both to mitotic chromosome condensation and dosage compensation.
Both of these epigenetic modifications can repress ER transcription and have been implicated in endocrine resistance [ 61].
Presence of both of these histone modifications (bivalency of histone 3, or coexpression of H3K4me3 and H3K27me3) allows a gene promoter to become activated or silenced, depending on the signal received [ 1].
The presence of both these modifications in unstimulated control cells may be attributed either to their being deposited here in previous rounds of transcription prior to quiescence, or to their being part of a transcription-independent pattern of pre-existing, possibly epigenetic, mechanism; there is no evidence either way at present.
Photocurrent maps of these modifications using both supra- and sub-bandgap photons are presented.
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