Sentence examples for both numerical and functional from inspiring English sources

In the setting of HIV infection, several reports have identified both numerical and functional defects in the DC and NK cell compartments [22] [29].

Previous work has suggested that colorectal cancer patients have both numerical and functional impairment in peripheral blood (Della Porta et al, 2005) and local tumour-infiltrating DCs (Schwaab et al, 2001; Dadabayev et al, 2004; Inoue et al, 2005; Cui et al, 2007; Yuan et al, 2008).

Both the numerical and functional balance between killer (e.g., CD4+ and CD8+ effectors) and regulatory T-cells in the pancreatic infiltrate determines the extent of β cell destruction [1].

The numerical and functional responses of colonizing wolves in Yellowstone's prey-rich environment were higher than expected and close to the maximum rates predicted prior to wolf restoration.

Studies in multiple human cancers and animal models revealed numerical and functional defects in iNKT cells.

Systemic numerical and functional iNKT cell defects have been observed in cancer patients.

We first sought to analyze whether prostate cancer-bearing mice exhibit numerical and functional iNKT cell defects comparable to those reported in cancer patients [6] [9].

Numerical and functional defects of invariant natural killer T cells (iNKT) have been documented in human and mouse cancers, resulting in a defect in IFN production in several malignancies.

A full exploration of the consequences of combined numerical and functional responses for the grouse hen-harrier system is beyond the scope of this paper and requires considerable further analysis that would need to take into account, for example, the rather complex nature of grouse population dynamics [42].

It is known that the effect of predator numerical and functional responses acting together is important in some systems [44] and this should also be considered in the multi-species context when populations of generalist predators are able to exploit a variety of prey [44].

Increased understanding of the mechanisms leading to the numerical and functional impairment of EPC is necessary.