In another 37 (9%) (range 0 60% across journals) images both a "normal" and one or more "abnormal" case were presented for comparison, but there was no comment/hint about the selection/representation of the shown abnormal cases.
There is no obvious reason for this phenomenon regarding clinical data since the cluster includes both normal and malignant tissues (two normal and five malignant).
For both normal and oblique wind directions, three layers of surroundings are required for regular street canyons with an aspect ratio H/W = 1.
The aim of the present review is to evaluate in detail the mechanisms of response of both normal and tumour cells to three chemotherapeutic antimetabolites, MTX, PALA and 5-FU, which are routinely used in the clinic either alone or in combination to treat some of the commonest solid tumours, e.g. breast, colon, gastric and head and neck.
Sorting of EGFR onto internal vesicles of both normal and abnormal MVBs was observed in three patient fibroblasts lines: two FTD-3 patients and one CHMP2BQ165X patient (Fig. 7).
Although this pathway has been widely demonstrated and seems to play a pivotal role in the control of p27 protein stability in both normal and cancer cell, at least two Skp2-independent pathways have been proved to induce p27 degradation during G1: the KPC1-KPC2 ubiquitin-ligases [14] and the activation of the Wnt-Cul4A pathway [15].
The quantification of cell nuclei allowed the differentiation of tumor tissue from both normal and hyperplastic tissue at all three degrees of magnification studied, indicating potential in clinical practice for the histological diagnosis of prostate cancer.
Target gene mRNA levels were very low (detectable but not quantifiable by real-time quantitative RT-PCR assay, Ct > 35) in both normal and tumoral breast tissues for seven genes (CYP1A1, CYP1A2, CYP2C9, CYP3A4, LPO, SULT2A1 and UGT1A1) out of the 27 xenobiotic-metabolizing enzyme genes.
Via FAIME, three independent prostate gene expression arrays with both normal and tumor samples were transformed into two distinct types of molecular pathway mechanisms: (i) the curated Gene Ontology (GO) and (ii) dynamic expression activity networks of cancer (Cancer Modules).
Both normal and abnormal tissues were sampled from five (CX, GA, DY, AZ, AM) out of seven patients.
