Sentence examples for both normal and SSc from inspiring English sources

Thus, TGF-β pathway is controllable in both normal and SSc fibroblasts.

Our results show that although a gene expression network responding to silica in both normal and SSc fibroblasts is controllable, the degree of controllability of this regulatory network between the normal and SSc fibroblasts is different.

The rank of controllability matrix of the system in the state-space model of this partial TGF-β pathway under perturbation of silica in both normal and SSc fibroblasts is equal to 5 which is the number of the state variables in the model.

Interestingly, ICAM-1 expression on both normal and SSc fibroblasts is activated by ET-1.

Both normal and SSc cells showed overproduction of intracellular ROS and upregulation of pERK levels after PMA incubation.

Moreover, TGFβ-induced matrix gene expression and ERK and p38 phosphorylation in both normal and SSc fibroblasts were also reduced.

We found that TSP1 expression and p-ERK activation were significantly increased in force-loaded fibroblasts isolated from both normal individuals and SSc patients.

We used the fibroblast populated collagen lattices (FPCL) system of matrix contraction to evaluate the contribution of TSP1 to the contractile activity of normal and SSc fibroblasts both basally and in response to TGFβ.

Additional details on the normal and SSc patients are provided on supplemental tables S1 and S2.

We have 5 pairs each of normal and SSc patients' samples.

This implies that the controllability of this network between the normal and SSc fibroblasts are differentiable.