Both sodium channel mutations and cell background contribute to neuronal function and clinical manifestations [ 9].
It is established that neuronal function and survival is intimately linked to both astroglial and microglial cells [ 30].
Calcium signals are crucial for just about every aspect of neuronal function, and nerve cells exhibit a sudden increase in calcium ion concentration when they begin to fire off nervous impulses.
Decreased proportion of GABA associated with age-related degradation of neuronal function and neuronal degenerative diseases [29].
A sufficient availability of cholesterol is necessary for normal neuronal function and morphology, neuronal cells' function is impaired not only due to lack but also surplus of cholesterol (Ko et al., 2005; Pooler et al., 2006).
PKA and, more recently, AKAPs, have been shown to be important in neuronal function and plasticity.
However, the mechanisms how mitochondrial fusion affects neuronal function and axonal survival remain unclear [28].
Neuronal and oligodendroglial apoptosis contributes to demyelination and Wallerian degeneration, and thereby affects neuronal function and survival after SCI.
Complementary approaches were used to explore the role of Dp71 in neuronal function and identify mechanisms by which Dp71 loss may impair neuronal and cognitive functions.
